SGLT2i for Mitral Regurgitation; Mining Angiograms With AI; Melatonin and CVD Risk?

— Recent developments of interest in cardiovascular medicine

MedpageToday
Cardio Break over a computer rendering of a heart.

The Apple Watch atrial fibrillation feature got added to FDA's list of qualified devices for use in clinical studies. (Mashable)

The SGLT2 inhibitor ertugliflozin (Steglatro) showed promise for the reduction of functional mitral regurgitation in some people with heart failure. (Circulation)

Although routinely measured in cardiovascular care, LDL cholesterol and triglyceride levels did not measure up to apolipoprotein B for predicting new-onset atherosclerotic cardiovascular disease. (European Heart Journal)

The overall incidence of ST-segment elevation myocardial infarction was nearly halved between 2004 and 2020, but racial and gender disparities persisted, researchers reported at the Society for Cardiovascular Angiography & Interventions (SCAI) annual conference.

Artificial intelligence (AI) algorithms were trained to automatically extract data from routine angiograms on left and right ventricular function, intracardiac filling pressures, and cardiac index, according to the AI-ENCODE study, also highlighted by SCAI.

The AI chatbot ChatGPT was able to pass an Interventional Cardiology Certification simulation exam but did not do as well as human fellows. (JACC: Cardiovascular Interventions)

Women who developed menopause before age 43 tended to have a greater risk of ischemic stroke, a meta-analysis found. (European Journal of Preventive Cardiology)

The new inflammatory composite score ICS5, a measure of inflammatory biomarkers centered on interleukin-18, predicted stroke and cognitive impairment in a sample of the Framingham Offspring Cohort. (Stroke)

Can attention deficit-hyperactivity disorder medications result in long-term cardiovascular harms? (Journal of the American College of Cardiology)

Self-reported use of melatonin supplements did not appear to have an effect on risk of type 2 diabetes or cardiovascular disease. (Lancet Diabetes & Endocrinology)

Treatment with inhaled seralutinib was associated with decreased pulmonary vascular resistance in people with pulmonary arterial hypertension receiving standard background therapy. (Lancet Respiratory Medicine)

Clusters of cardiometabolic disease may be identified at the neighborhood level using satellite photos capturing health-related built environment features such as highways and baseball parks. (JAMA Cardiology)

Researchers were able to create super-resolution images of myocardial vascular structure and flow using transthoracic ultrasound localization microscopy, a technique relying on gas-filled bubbles and a breath hold by the subject. (Nature Biomedical Engineering)

A North Carolina cardiologist was arrested at work and charged with indecent liberties with a child and first-degree sexual offense. (WECT)

After collapsing during a soccer game in December and getting a defibrillator implant, Tom Lockyer said he is "at peace" with potentially retiring from the sport. (AP)

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    Nicole Lou is a reporter for MedPage Today, where she covers cardiology news and other developments in medicine. Follow