ScienceDaily

A cutting-edge therapy using base-edited immune cells is offering a major breakthrough for patients with one of the toughest forms of blood cancer, T-cell acute lymphoblastic leukaemia. By precisely rewriting tiny sections of DNA, scientists at UCL and Great Ormond Street Hospital created universal CAR T-cells capable of targeting the cancer without harming themselves—a long-standing challenge in…

Scientists discovered that the protein RPA plays a critical and previously unconfirmed role in stimulating telomerase to maintain long, healthy telomeres. When RPA malfunctions, telomeres can shorten dangerously, leading to serious diseases.

Scientists tracking young Arizona Bald Eagles found that many migrate north during summer and fall, bucking the traditional southbound pattern of most birds. Their routes rely heavily on historic stopover lakes and rivers, and often extend deep into Canada. As the eagles mature, their flights become more precise, but they also encounter significant dangers like electrocution and poisoning. These …

A new economic modeling tool is helping Maine kelp farmers identify cost-saving strategies with remarkable precision. By analyzing farm design, weather, vessel types, and processing methods, it highlights how decisions ripple through overall profitability. When tested, the tool demonstrated that simple redesigns and mechanization could dramatically reduce production costs. Its findings could resh…

Scientists developed a high-performance hydrogen-production catalyst using lignin, a common waste product from paper and biorefinery processes. The nickel–iron oxide nanoparticles embedded in carbon fibers deliver fast kinetics, long-term durability, and low overpotential. Microscopy and modeling show that a tailored nanoscale interface drives the catalyst’s strong activity. The discovery points …

Scientists have uncovered that some atoms in liquids don't move at all—even at extreme temperatures—and these anchored atoms dramatically alter the way materials freeze. Using advanced electron microscopy, researchers watched molten metal droplets solidify and found that stationary atoms can trap liquids in tiny “atomic corrals,” keeping them fluid far below their normal freezing point and giving…

Northwestern scientists have created the fastest-ever hepatitis C diagnostic, delivering accurate results in only 15 minutes. The test uses the DASH rapid PCR system, originally developed for COVID, but adapted for whole blood samples. Independent testing showed 100% agreement with existing commercial platforms. Its speed could transform how quickly patients begin treatment.

Researchers uncovered how shifting levels of a brain protein called KCC2 can reshape the way cues become linked with rewards, sometimes making habits form more quickly or more powerfully than expected. When this protein drops, dopamine neurons fire more intensely, strengthening new associations in ways that resemble how addictive behaviors take hold. Rat studies showed that even brief, synchroniz…

Scientists discovered that certain cancer cells use a low-level activation of a DNA-dismantling enzyme—normally seen in cell death—to survive treatment. Instead of dying, these “persister cells” leverage this sublethal signal to regrow. Because the mechanism is non-genetic, it appears much earlier than typical resistance mutations. Targeting this enzyme could help stop tumors from returning.

Researchers have uncovered surprising evidence that the deep ocean’s carbon-fixing engine works very differently than long assumed. While ammonia-oxidizing archaea were thought to dominate carbon fixation in the sunless depths, experiments show that other microbes—especially heterotrophs—are doing far more of the work than expected. This discovery reshapes our understanding of how carbon moves th…

Obesity accelerates the rise of Alzheimer’s-related blood biomarkers far more rapidly than previously recognized. Long-term imaging and plasma data show that obese individuals experience much faster increases in proteins linked to neurodegeneration and amyloid buildup. Surprisingly, blood tests detected these changes earlier than PET scans. The results point to obesity as a major, modifiable cont…

Uranus and Neptune may not be the icy worlds we’ve long imagined. A new Swiss-led study uses innovative hybrid modeling to reveal that these planets could just as easily be dominated by rock as by water-rich ices. The findings also help explain their bizarre, multi-poled magnetic fields and open the door to a wider range of possible interior structures. But major uncertainties remain, and only fu…

Researchers discovered that a long-misunderstood protein plays a key role in helping chromosomes latch onto the right “tracks” during cell division. Instead of acting like a motor, it works more like a stabilizer that sets everything up correctly from the start. This simple shift in understanding changes how scientists view one of the most important steps in biology. It also highlights a potentia…

A Virginia Tech study shows that ultra-processed foods may influence adolescents differently from slightly older young adults. Participants aged 18 to 21 ate more at a buffet and snacked even when not hungry after two weeks on an ultra-processed diet. Because eating without hunger predicts future weight gain, these findings hint at a heightened vulnerability during late adolescence.

New research reveals that Earth’s solid inner core is actually in a superionic state, where carbon atoms flow freely through a solid iron lattice. This unusual behavior makes the core soft, matching seismic observations that have puzzled scientists for decades. The mobility of these light elements may also contribute energy to Earth’s magnetic field. The findings reshape models of Earth’s interio…