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MedPageToday

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Putting Breaking Medical News Into Practice(TM)

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Life & Style → Health

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Novel Drug Reduces Steroid Need in Congenital Adrenal Hyperplasia

23:35
(MedPage Today) -- BOSTON -- Investigational crinecerfont reduced the need for glucocorticoids in adults and kids with congenital adrenal hyperplasia (CAH), two phase III trials found. In the adult trial of 182 patients, those on crinecerfont...

'More and More Patients in Less and Less Time': What We Heard This Week

22:32
(MedPage Today) -- "It feels like we're being asked to see more and more patients in less and less time." -- Meghan Lelonek, MD, a hospitalist with Sound Physicians and PeaceHealth in Washington, who helped lead a unionization effort. "School...

'Practice Changing' Trial for Inoperable Locally Advanced NSCLC

20:25
(MedPage Today) -- CHICAGO -- Patients without disease progression following chemoradiotherapy for unresectable stage III non-small cell lung cancer (NSCLC) should receive osimertinib (Tagrisso) if they harbor EGFR mutations, experts said here...

Intralesional Therapy for Melanoma Effective, May Have Systemic Activity

20:25
(MedPage Today) -- CHICAGO -- Preoperative intralesional treatment with a dual antibody-cytokine fusion significantly improved relapse-free survival (RFS) in locally advanced melanoma versus surgery alone, a randomized trial showed. Median RFS...

Blenrep-Based Regimen Yields PFS Benefit in Relapsed/Refractory Myeloma

20:25
(MedPage Today) -- CHICAGO -- Progression-free survival (PFS) was significantly higher with belantamab mafodotin (belamaf; Blenrep) combined with pomalidomide (Pomalyst) and dexamethasone (BPd), compared with standard-of-care pomalidomide, bortezomib...

Virtual and In-Person Palliative Care Equally Beneficial in Advanced Lung Cancer

19:21
(MedPage Today) -- CHICAGO -- Early palliative care delivered via video was as effective as in-person visits on quality-of-life (QoL) measures among patients with advanced lung cancer, according to the REACH-PC trial. Further, patient and caregiver...

Fast-Food Medicine: EDs Desperately Need a New Model of Care

18:49
(MedPage Today) -- Sunday, 7 a.m.: On any given Sunday morning, I expect to arrive for my emergency department (ED) shift to a department in disarray. There's a certain colliding of worlds that happens -- the wreckage of Saturday night debauchery...

No Survival Advantage With Sacituzumab Over Chemo in Previously Treated NSCLC

15:37
(MedPage Today) -- CHICAGO -- Treatment with single-agent sacituzumab govitecan (Trodelvy) offered no survival advantage over docetaxel in patients with advanced non-small-cell lung cancer (NSCLC) previously treated with platinum-based chemotherapy...

Subcutaneous Amivantamab Plus Lazertinib Non-Inferior to IV Dosing in NSCLC

0:34
(MedPage Today) -- CHICAGO -- Subcutaneous amivantamab (Rybrevant) was non-inferior to IV amivantamab for pre-treated patients with refractory EGFR-mutated, advanced non-small cell lung cancer (NSCLC), with the suggestion of a possible survival...

Novel Bispecific in EGFR-Mutant Lung Cancer Boosts PFS After Targeted Agents

1.června
(MedPage Today) -- CHICAGO -- An investigational bispecific antibody targeting PD-1 and VEGF significantly decreased the risk of disease progression or death in patients with metastatic EGFR-mutant non-small cell lung cancer (NSCLC) who progressed...

Kinder, Gentler Regimen for Classical Hodgkin Prevails in Randomized Trial

1.června
(MedPage Today) -- CHICAGO -- Replacing chemotherapy with a targeted agent resulted in a better tolerated regimen for advanced classical Hodgkin lymphoma (cHL) with no loss in efficacy, according to a randomized study reported. The estimated 4...

Hypertension After Kidney Donation; Statins in Old and Very Old People

1.června
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center...

Where Are All the Male Nurses?

1.června
(MedPage Today) -- Nurses are critical to a functioning healthcare system, yet our country is currently facing a nursing shortage that is projected to intensify in the next few years. The shortage is not just a statistic for me; it is a reality...

Guillain-Barre Syndrome Rates After RSV Shots in Sync With Trial Data, CDC Says

1.června
(MedPage Today) -- Reports of Guillain-Barré syndrome (GBS) following respiratory syncytial virus (RSV) vaccination in adults ages 60 and up were higher than expected, but the vaccine's benefits still outweigh any small potential risk, according...
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