High BMI and Longevity; Infective Endocarditis in Young Whites; Damar Hamlin Update

— Recent developments of interest in cardiovascular medicine

MedpageToday
Cardio Break over a computer rendering of a heart.

A higher body mass index (BMI) and lower waist circumference were causally associated with longevity for people older than 80, according to a Mendelian randomization study. (European Heart Journal)

Disrupted deep sleep, captured from overnight polysomnograms, may be a predictor of heart disease and cardiovascular mortality. (Journal of the American College of Cardiology)

For heart attack patients undergoing percutaneous coronary intervention, the sequence of 9-12 months of dual antiplatelet therapy followed by 9 months of clopidogrel (Plavix) monotherapy appeared to balance both high bleeding and ischemic risks, a randomized trial showed. (JAMA Cardiology)

Thoracic artery calcium on chest CT correlates with coronary artery calcium on cardiac CT, but is no replacement as a risk predictor. (Heart)

Stroke patients undergoing mechanical thrombectomy who tested positive for COVID-19 had similar outcomes regardless of COVID-19 vaccination. (Journal of the American Heart Association)

Long-term blood pressure measures were positively associated with intracerebral hemorrhage (ICH). (European Journal of Preventive Cardiology)

IV tranexamic acid administered within 2 hours of an ICH failed to reduce hematoma growth in a phase II trial. (Lancet Neurology)

Opioid use disorder is suspected of driving the spike in infective endocarditis among young white people in New York and Florida. (Circulation)

Targeted, individualized electronic health record alerts did not significantly boost intensification of lipid-lowering therapies in a cluster-randomized trial. (Circulation: Cardiovascular Quality and Outcomes)

Atrial fibrillation was tied to cardiovascular events and years lost in people younger than 65 years. (Circulation: Arrhythmia and Electrophysiology)

Permanent pacemaker implantation was a red flag for survival and heart failure outcomes after cardiac surgery, according to a meta-analysis. (Journal of Thoracic and Cardiovascular Surgery)

Outside oncology, most surrogate markers used as primary trial endpoints did not correspond strongly with clinical outcomes in meta-analyses. (JAMA)

Meta-analysis results put overall incidence of chemotherapy-related cardiac dysfunction in cancer patients at an estimated 63.21 per 1,000 person-years. (Clinical Cardiology)

Damar Hamlin shares his health routine following his cardiac arrest on the field during a football game in 2023. (Parade)

A New Jersey cardiologist had his medical license permanently revoked after criminal charges related to malpractice and sexual misconduct. (NorthJersey.com)

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    Nicole Lou is a reporter for MedPage Today, where she covers cardiology news and other developments in medicine. Follow