Ozempic Price Cut; Hypoparathyroidism Tx Fast Tracked; Halle Berry's Menopause Bill

Novo Nordisk cut the price of its blockbuster weight-loss and diabetes drug semaglutide (Wegovy, Ozempic). (Reuters)

In adults with increased fracture risk, once-weekly 1-mg semaglutide did not increase bone formation based on the bone formation marker plasma-PINP compared with placebo, according to a phase II trial in Denmark. (eClinicalMedicine)

The FDA granted a fast track designation to eneboparatide for hypoparathyroidism, said developer Amolyt Pharma.

Surgical premature menopause was linked with higher prevalence of severe musculoskeletal discomfort and sarcopenia, a cross-sectional study showed. (Menopause)

"I call it my foggy days." Actress Halle Berry and U.S. senators unveiled a $275 million bill that aims to boost menopause care. (Washington Post)

Compared with mothers without a history of gestational diabetes, those with a history had a 50% increased risk of developing non-alcoholic fatty liver disease (NAFLD) up to 25 years later, while their offspring had over a twofold higher risk for NAFLD development, according to a systematic review and meta-analysis. (eClinicalMedicine)

In people with uncontrolled type 2 diabetes already on oral antidiabetics with or without basal insulin or GLP-1 receptor agonists, adding iGlarLixi -- a fixed combination of insulin glargine 100 U/mL and lixisenatide -- was tied to reductions in HbA1c levels, with a low rate of severe hypoglycemia, a prospective observational study showed. (Diabetes, Obesity and Metabolism)

Amgen said it is scrapping its investigational obesity pill and will move forward with its injectable agent, maridebart cafraglutide known as MariTide. (CNBC)

In a head-to-head trial of insulin sensitizers, pioglitazone (Actos) outperformed metformin prior to in vitro fertilization cycles in polycystic ovarian syndrome-related infertile women, thus leading to a higher pregnancy rate. (Annals of Medicine & Surgery)

Denmark plans to have people with type 2 diabetes start cheaper drugs before letting them get GLP-1 receptor agonists like semaglutide. (Reuters)

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