Scientists have designed an oral
capsule which can deliver
insulin and other drugs — that usually have to be injected — to the lining of the
small intestine and release them for uptake into the
bloodstream.
Many drugs, especially those made of proteins, cannot be taken orally because they are broken down in the
gastrointestinal tract before they can take effect.
The researchers at MIT, working with scientists from Danish pharmaceutical company
Novo Nordisk, have designed a new
drug capsule that can carry insulin or other protein drugs and protect them from the harsh environment of the gastrointestinal tract.
It breaks down to reveal dissolvable microneedles carrying that attach to the intestinal wall and release drug.