Ozempic's New Heart Indication; Pesticides Shave Kids' IQ Points

The FDA expanded the label of Novo Nordisk's injectable glucagon-like peptide-1 (GLP-1) analogue semaglutide (Ozempic), which now carries an indication for major adverse cardiovascular event reduction in adults with type 2 diabetes based on results from SUSTAIN 6.

Chiasma announced the FDA accepted a resubmitted application of its adult acromegaly treatment octreotide (Mycapssa).

Exposure to chemicals found in flame retardants and pesticides was tied to lower IQ scores in children. (ScienceDaily)

Women who reported having less sex tended to transition to menopause at an earlier age. "The findings of our study suggest that if a woman is not having sex, and there is no chance of pregnancy, then the body 'chooses' not to invest in ovulation, as it would be pointless," lead author Megan Arnot, a PhD candidate at University College London, said in a statement. (Royal Society Open Science)

A Canadian study suggested that investing in improved pre- and post-operative care for patients undergoing bariatric surgery can help save nearly 30% in healthcare costs. (JAMA Network Open)

Around 20% of young adults in the U.K. had fatty liver disease, driven by the obesity epidemic. "This age group remains a blind spot for clinicians, as they are typically considered a 'healthy' age group that are rarely studied," said lead author Kushala Abeysekera, MBBS, of the University of Bristol, in a statement. (Lancet Gastroenterology & Hepatology)

In related news, 9/11 World Trade Center responders had more than a threefold higher rate of moderate-to-severe hepatic steatosis. (Clinical Imaging)

Exonate and Janssen announced a partnership to develop an eye drop for diabetic macular edema.

Comment