A Grindr hook-up ended in bloodshed in the Bronx Sunday after a dispute over sex acts drove a man wearing a bra, panties and dress to fatally slash the man he met on the dating app with a machete, cops said Monday.

Police were called to 315 E. 206th St. around 7 p.m. Sunday after alleged killer Juan Alonso’s roommate came home to find him holding the machete while standing over the dead man, who was completely naked, according to cops.

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Alonso met the victim on the app, a popular meeting place for gay men. He was taken into custody, psychologically evaluated, and charged with murder, manslaughter and criminal possession of a weapon, cops said.

Officials are investigating whether there was a “dispute over not liking certain sex activities and it escalated,” a police spokesman said.

The dead man’s identity also wasn’t immediately released.

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“The perp is not in his right mind,” a police source said. “He might have taken drugs.”