THE MEDICAL NEWS

The CARDIO-TTRansform trial investigating eplontersen in patients with transthyretin-mediated amyloid cardiomyopathy did not meet its primary efficacy endpoint, according to results presented in a Hot Line session today at ESC Congress 2026.

LMU researchers identify a molecular mechanism that enables single-celled parasites to switch on the machinery they need to move and invade host cells.

When a myocardial infarction, such as a heart attack, occurs, being able to classify its type can improve diagnosis and treatment.

The first-ever European Society of Cardiology Guidelines on the management of cardiovascular disease and chronic kidney disease have been developed in collaboration with the European Renal Association.

The European Society of Cardiology (ESC) Guidelines on cardiac rehabilitation have been published online today in the European Heart Journal.

Heart failure hospitalization risk increases after short-term exposure to cold spells, lower ambient temperatures and higher ambient temperatures, according to a study published in JACC, the flagship journal of the American College of Cardiology, and simultaneously presented at ESC Congress 2026.

Amyotrophic lateral sclerosis (ALS) is a severe neurological disease that destroys nerve cells responsible for muscle movement.

This narrative review examines how psychobiotics may influence anxiety, depression, bipolar disorder, and schizophrenia through gut-brain pathways involving neurotransmitters, inflammation, immune regulation, gut barrier function, and stress signaling. Specific Lactobacillus and Bifidobacterium strains showed encouraging effects, but wide differences in strains, doses, populations, and study desi…

In a large Australian cohort of adults with hypertension, use of blood-brain barrier-crossing antihypertensive medications was associated with a lower risk of dementia and mortality than use of non-crossing drugs. The association was strongest for beta-blockers and angiotensin II receptor blockers, although the observational design means the findings cannot establish causality.