THE MEDICAL NEWS |
Popis: from News-Medical.Net - Latest Medical News and Research from Around the World
|
||||||
Scientists uncover promising therapeutic target for autoimmune disease affecting the brain4:05 Scientists have identified a promising target for treatment of a devasting autoimmune disease affecting the brain. Pregnant individuals with inflammatory bowel disease show heightened vaginal inflammation4:05 Pregnant individuals with inflammatory bowel disease (IBD) have higher levels of pro-inflammatory immune molecules, known as cytokines, in their vaginal mucosa than their healthy counterparts, according to a new study published January 14, 2026 in the open-access journal PLOS One by Ana Maldonado-Contreras of University of Massachusetts Chan Medical School, U.S., and colleagues. Study reveals genetic signatures linked to HIV-related cognitive impairment4:05 Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures associated with HIV infection that may contribute to the cognitive impairment that often occurs in people living with HIV, even when the virus is controlled. Polyamines reshape protein phosphorylation to guide key cellular fate decisions3:32 Polyamines are small molecules naturally present in all cells and are critical in guiding cellular decisions, whereas an alteration in the abundance of these metabolites is invariably observed in pathological scenarios such as cancer or aging. Rare immune events link Epstein Barr virus to early multiple sclerosis damage3:32 Autoimmune diseases such as multiple sclerosis arise when the immune system turns against the body itself. Bradycardia emerges as key clinical sign of xylazine-opioid overdose3:32 Researchers have identified bradycardia-an abnormally low heart rate–as a symptom of xylazine-opioid overdose. CRISPR-Cas3: A safer gene-editing tool shows promise for transthyretin amyloidosis treatment20:41 Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin amyloidosis (ATTR) is a progressive disorder involving amyloid deposits of misfolded transthyretin (TTR) proteins. Engineered vessels boost retinal organoid function, enabling advanced disease modeling20:06 Until now, it has been difficult to maintain retinal ganglion cells deep inside organoids over extended periods. The supply of nutrients and oxygen in the densely packed tissues is limited, leading to cell death. Age-tailored therapies needed for treating the young and old with sepsis20:06 Dealing with an infection isn't as straightforward as simply killing the pathogen. The body also needs to carefully steer and monitor its immune response to prevent collateral damage. Novel liquid biopsy technology could advance cancer diagnostics and monitoring20:06 A novel liquid biopsy technology is set to advance cancer diagnostics and monitoring by overcoming the long-standing challenge of simultaneously achieving high sensitivity, broad coverage, and simple workflow. |