THE MEDICAL NEWS |
Popis: from News-Medical.Net - Latest Medical News and Research from Around the World
|
||||||
Living near a dry cleaner may come with an unexpected Parkinson’s disease link8:11 A nationwide case-control study of older U.S. Medicare beneficiaries found that living closer to a dry-cleaning establishment was associated with higher odds of incident Parkinson’s disease, with the strongest association among people living within 0.1 mile. Researchers discover smart molecular glue that activates inside oxidative cancer cells8:11 Investigators at Dana-Farber Cancer Institute have developed a platform for systematically discovering molecular glues that could become protein degradation drug candidates. Disrupted RNA methylation pathway accelerates Alzheimer’s and Parkinson’s risks7:39 A growing understanding of RNA biology is reshaping how scientists view the relationship between environmental toxicants, brain development, and neurodegenerative disease. Scientists map key differences in stem cell potency for treating knee osteoarthritis7:39 Knee osteoarthritis (KOA) affects more than 1 in 10 people over 40 years of age, impairing patients' mobility and quality of life. Fine particle pollution raises rheumatoid arthritis flare risk and disease activity7:39 Higher ambient PM2.5 exposure was associated with increased rheumatoid arthritis disease activity and a greater likelihood of flares in a four-year South Korean cohort of 1,070 patients. The association appeared stronger with sustained exposure over approximately two weeks or longer, while women and nonsmokers showed more pronounced links between PM2.5 and DAS28-CRP. Low-fat vegan diet helps people lose weight without cutting back on food7:39 A low-fat vegan diet lowers the energy density of the foods people eat by roughly 30%, allowing them to eat satisfying amounts of food while taking in fewer calories and losing weight-without deliberately restricting calories-according to new research published in JAMA Network Open. Metabolic stress triggers long-lasting immune system changes in diabetes patients7:07 A growing understanding of trained immunity, a form of long-lasting immune system adaptation, is reshaping how scientists view diabetes and its many complications. New research highlights carbohydrate role in early human brain development7:06 Fruit, honey and other naturally sweet foods may have helped fuel the evolution of the human brain, according to new research from the University of Sydney and the University of Glasgow. Genetic analysis of 1 million people points to FNIP1 as a promising metabolic target7:06 Mega-scale exome sequencing of 1,032,116 people identified 59 independent genes linked to the TG:HDL ratio, including 44 rare-coding associations not detected in the previous largest analysis. Ultra-rare FNIP1 loss-of-function variants were associated with favorable fat distribution, lower liver fat and glycemia, and around 60% lower odds of a composite cardiometabolic disease outcome. Severe COVID-19 reactivates dormant viruses and may leave a lasting viral signature6:35 A longitudinal study of 1,154 hospitalized COVID-19 patients found widespread reactivation of chronic Herpesviridae and Anelloviridae, with distinct viral patterns linked to disease severity, inflammation, and clinical outcomes. Anelloviridae also persisted during convalescence and were associated with physical deficits in long COVID, although the study did not establish causation. |