THE MEDICAL NEWS

This perspective argues that Parkinson’s disease may involve functional iron deficiency, where bioavailable iron is limited despite normal or elevated total iron in the brain. The authors propose that iron sequestration, not iron toxicity alone, may impair dopamine synthesis and neuronal survival.

Enveda, a multi-asset clinical-stage biotech company pioneering the discovery and development of a new generation of small-molecule drugs derived from life’s chemistry, has announced that the US Food and Drug Administration (FDA) has cleared the Company’s Investigational New Drug (IND) application for ENV-6946.

This comprehensive review synthesizes a decade of human and animal research to explain how the gut and brain communicate through hormonal, neural, immune, and microbial pathways. It highlights how disruptions in these pathways contribute to gastrointestinal, metabolic, and neurological disorders, and how modern therapies are beginning to exploit gut–brain signaling for clinical benefit.

This review synthesizes clinical, genetic, and mechanistic evidence showing that suPAR and related uPAR fragments are strongly associated with kidney, cardiovascular, and metabolic disease risk. It highlights suPAR as a stable biomarker of innate immune activation with potential pathogenic roles, while underscoring major gaps in assay standardization and therapeutic validation.

For centuries, Borago officinalis - commonly known as Borage or the Starflower - has been a staple of traditional medicine.

Researchers at The University of Texas at El Paso have found unusually high levels of parasitic infection in the insects that transmit Chagas disease in the Borderlands.

Sleeping in on the weekend to catch up on sleep lost during the week may be good for adolescents' mental health, according to new research by the University of Oregon and the State University of New York Upstate Medical University.

A new database targeting chronic urinary tract infections (UTIs) – a long-overlooked condition that may begin in childhood – is set to help researchers uncover why millions of women and girls worldwide suffer from infections that defy treatment and stump microbiologists.