THE MEDICAL NEWS

In a mouse model of tauopathy, conventional type 1 dendritic cells (cDC1s) cross-presented brain-derived antigens in deep cervical lymph nodes, priming CD8+ T cells that accumulated in the brain and promoted neurodegeneration. Disrupting cDC1s or their cross-presentation activity reduced CD8+ T-cell infiltration and protected against neuronal loss, while human primary tauopathy samples also showe…

Smoking is not social and leads to increased loneliness, according to a large Europe-wide study presented at the European Respiratory Society (ERS) Congress in Barcelona, Spain.

A systematic review of 11 observational studies representing more than 4.9 million patients found that GLP-1 receptor agonists were generally associated with neutral or potentially protective psychiatric outcomes, although one obesity-focused cohort reported increased risks of depression, anxiety, and suicidal behavior. Direct evidence for antidepressant effects remains limited, with only one cro…

A clinical trial for patients with chronic obstructive pulmonary disease (COPD) shows that laughter therapy can reduce breathing difficulties and is as effective as more traditional breathing exercises. The research is presented at the European Respiratory Society (ERS) Congress in Barcelona, Spain.

In a third of cases, AI chatbots wrongly reassure sleep apnea patients that their symptoms are not serious, discouraging them from seeking a referral to a specialist, according to research presented at the European Respiratory Society (ERS) Congress in Barcelona, Spain.

Common bacteria found in classroom dust are associated with reduced lung function in children according to research presented at the European Respiratory Society (ERS) Congress in Barcelona, Spain.

A 24-week pilot randomized trial found that both traditional Hatha yoga and a faster, cognitively demanding YogaCue program were associated with improvements in cognitive and physical performance in independently living older adults. YogaCue showed promising additional gains in verbal and episodic memory, aerobic fitness, and lower-body power, although the small study could not establish clear su…

In mouse models, prophylactic psilocybin prevented or reduced multiple features of chemotherapy-induced peripheral neuropathy, with cycle-matched dosing sustaining protection during repeated cisplatin exposure without measurably affecting tumor growth. Experiments in human-derived sensory neurons and ex vivo peripheral nerves linked the effect to 5-HT2A-dependent preservation of mitochondrial tra…

From coffee and energy drinks to bubble tea and soft drinks, an analysis of more than 2 million people reveals a surprisingly complex relationship between what we drink and mental health.