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Automated system improves deep learning accuracy in chest radiography analysis24.prosince Researchers at Osaka Metropolitan University have discovered a practical way to detect and fix common labeling errors in large radiographic collections. By automatically verifying body-part, projection, and rotation tags, their research improves deep-learning models used for routine clinical tasks and research projects. Researchers develop mild mitochondrial uncouplers for obesity treatment24.prosince Researchers have developed experimental drugs that encourage the mitochondria in our cells to work a little harder and burn more calories. The findings could open the door to new treatments for obesity and improve metabolic health. Aptamer Group and Alphazyme execute licensing agreement for synthetic aptamer-based enzyme modulation in hot-start PCR24.prosince Aptamer Group plc, a developer of synthetic oligonucleotide-based binding reagents for life sciences applications, and Alphazyme LLC (Alphazyme), a Maravai LifeSciences company specializing in enzymes for molecular biology, have executed a licensing agreement for a proprietary Optimer® binder developed for hot-start polymerase chain reaction (PCR) applications. Alcohol consumption plays a major role in India’s mouth cancer burden24.prosince Even a low daily intake of alcohol--just 9 g or around one standard drink-is linked to a 50% heightened risk of mouth (buccal mucosa) cancer in India, with the greatest risk associated with locally brewed alcohol, finds a large comparative study, published online in the open access journal BMJ Global Health. Restoring brain energy balance reverses Alzheimer’s disease in mouse models24.prosince For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery. Discovery of a fat-regulating enzyme points to a new obesity therapy24.prosince Obesity is a global epidemic and a major cause of morbidity and mortality because it increases the risk for comorbidities, including heart disease and fatty liver disease (MASLD). Artificial intelligence improves risk stratification in oropharyngeal cancer24.prosince A team led by investigators at Mass General Brigham and Dana-Farber Cancer Institute has developed and validated an artificial intelligence (AI)–based noninvasive tool that can predict the likelihood that a patient's oropharyngeal cancer-a type of head and neck cancer that develops in the throat-will spread, thereby signaling which patients should receive aggressive treatment. Older age affects functional recovery after spinal cord injury24.prosince A new study published on December 23, 2025, in Neurology, the medical journal of the American Academy of Neurology, looks at how age may affect recovery for people with spinal cord injuries. Paternal microplastic exposure alters metabolic health in offspring24.prosince A study led by biomedical scientists at the University of California, Riverside, has shown for the first time that a father's exposure to microplastics (MPs) can trigger metabolic dysfunctions in his offspring. Study validates OVCAR3 as a model for high-grade serous ovarian cancer24.prosince A new research paper was published in Volume 12 of Oncoscience on October 14, 2025, titled "Bridging clinical insight and laboratory model in high-grade serous ovarian carcinoma (HGSOC) using DNA sequencing-based profiling of TP53." |
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