THE MEDICAL NEWS

A nationwide case-control study of older U.S. Medicare beneficiaries found that living closer to a dry-cleaning establishment was associated with higher odds of incident Parkinson’s disease, with the strongest association among people living within 0.1 mile.

Investigators at Dana-Farber Cancer Institute have developed a platform for systematically discovering molecular glues that could become protein degradation drug candidates.

A growing understanding of RNA biology is reshaping how scientists view the relationship between environmental toxicants, brain development, and neurodegenerative disease.

Knee osteoarthritis (KOA) affects more than 1 in 10 people over 40 years of age, impairing patients' mobility and quality of life.

Higher ambient PM2.5 exposure was associated with increased rheumatoid arthritis disease activity and a greater likelihood of flares in a four-year South Korean cohort of 1,070 patients. The association appeared stronger with sustained exposure over approximately two weeks or longer, while women and nonsmokers showed more pronounced links between PM2.5 and DAS28-CRP.

A low-fat vegan diet lowers the energy density of the foods people eat by roughly 30%, allowing them to eat satisfying amounts of food while taking in fewer calories and losing weight-without deliberately restricting calories-according to new research published in JAMA Network Open.

A growing understanding of trained immunity, a form of long-lasting immune system adaptation, is reshaping how scientists view diabetes and its many complications.

Mega-scale exome sequencing of 1,032,116 people identified 59 independent genes linked to the TG:HDL ratio, including 44 rare-coding associations not detected in the previous largest analysis. Ultra-rare FNIP1 loss-of-function variants were associated with favorable fat distribution, lower liver fat and glycemia, and around 60% lower odds of a composite cardiometabolic disease outcome.

A longitudinal study of 1,154 hospitalized COVID-19 patients found widespread reactivation of chronic Herpesviridae and Anelloviridae, with distinct viral patterns linked to disease severity, inflammation, and clinical outcomes. Anelloviridae also persisted during convalescence and were associated with physical deficits in long COVID, although the study did not establish causation.