THE MEDICAL NEWS

A narrative review links reduced SCFA-producing gut bacteria and altered microbial metabolism with Alzheimer’s disease, while early evidence suggests similar changes may appear before cognitive symptoms. Mediterranean, DASH, MIND, and prudent diets are associated with beneficial microbial profiles, but direct evidence connecting diet, the microbiome, and amyloid pathology remains limited.

Researchers analyzing 1,518 South African household participants found that higher pre-season antibody titers were associated with lower infection risk for three of four influenza viruses studied. Children remained more susceptible after accounting for measured exposure and antibody titers, while younger children shed viral RNA longer than older adults.

Researchers surveyed 10,618 adults across 1,372 localities in the world’s 10 most populous countries and matched their responses with average 2019-2021 PM2.5 concentrations. Higher PM2.5 exposure was associated with lower air-quality knowledge but greater concern and more frequent protective behaviors, with patterns differing across demographic groups.

An exploratory randomized trial found that 200 g of raw tomatoes plus 50 g of tomato sauce daily for six weeks produced a greater reduction in CAP-defined hepatic steatosis than a tomato-free diet in adults with MASLD. The improvement occurred without major weight or metabolic changes, but larger and longer trials are needed to confirm its clinical significance.

An evidence review of international research suggests widespread misconceptions within the medical community about early milk production, pacifiers and breast pumps may be undermining breastfeeding success in the critical first days after birth.

A traditional Japanese medicine used for obesity may do more than support weight loss. Researchers at the University of Osaka, working with Kobayashi Pharmaceutical Co., Ltd. investigated whether Bofutsushosan could protect aging tissues from fibrosis - the excessive buildup of scar-like tissue that can make organs stiff and less functional.

Extreme fatigue, a racing pulse, shortness of breath, brain fog, aching joints-the symptoms of long COVID can vary widely, change unpredictably, and be difficult to even recognize as signs of the condition.

In 3,895 older adults, moderate daytime cortisol variability was associated with better cognition and slower decline, while the highest daily cortisol exposure was linked to poorer cognition and faster decline. Cortisol patterns differed between Black and White participants, but their relationships with cognition were similar, and none predicted incident Alzheimer’s disease.