THE MEDICAL NEWS |
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Weight gain timing affects long-term health outcomes20:41 When in life we gain weight can have a significant impact on our health many years later. In a study involving over 600,000 people, researchers at Lund University in Sweden have investigated how changes in weight between the ages of 17 and 60 are linked to the risk of dying from various diseases Letrozole monotherapy falls short in ovarian cancer clinical trial19:05 Late breaking results from the phase III NRG GY019 trial indicate that letrozole monotherapy (L) did not demonstrate non inferiority to paclitaxel/carboplatin followed by letrozole (PC/L) for progression free survival (PFS) in patients with newly diagnosed stage II-IV low grade serous carcinoma of the ovary or peritoneum. Nanodisc technology improves study of viral proteins for vaccines18:33 Viruses are masters at invading our cells thanks to specialized proteins that coat their surfaces. When scientists design vaccines, they often create versions of these viral surface proteins to study how our immune systems might respond. Study links COVID-19 infection to increased lung cancer risk16:26 New findings from researchers at the Marshall University Joan C. Edwards School of Medicine and The Hebrew University of Jerusalem have identified a potential association between COVID-19 and increased lung cancer risk, driven by underlying biological mechanisms in the lung. Genetic variants may reduce effectiveness of popular diabetes drugs15:54 More than a quarter of people with Type 2 diabetes take GLP-1 receptor agonists, but the popular diabetes drugs might not work as well for people who have certain genetic variants, according to a new study by Stanford Medicine scientists and their collaborators. New target CD43 may improve leukemia immunotherapy outcomes15:54 Macrophages, much like Alice of "Alice in Wonderland," recognize and consume tumor cells that display "eat me" surface markers. Mezagitamab shows promise in treating immune thrombocytopenia patients14:18 Results from a phase 2 clinical trial designed and overseen by researchers at Mass General Brigham Cancer Institute show that the investigational medication mezagitamab can effectively boost platelet counts in patients with immune thrombocytopenia (ITP), an autoimmune disease characterized by elevated platelet destruction and reduced platelet production that increases bleeding risk and compromises quality of life. Study uncovers key structure in fatal Borna disease virus 114:18 Cases of Borna disease virus 1, or BoDV-1, are extremely rare in humans, but in those who develop disease the outcome is severe, almost always resulting in fatal encephalitis or inflammation in the brain. Maternal signals help synchronize babies’ circadian rhythms before birth13:45 Humans and most other organisms have internal biological clocks that track the daily cycle of sunrise and sunset. These clocks help time our sleep, metabolism and other essential body functions over the course of a day, creating daily patterns called circadian rhythms. New project aims to improve aggressive breast cancer diagnosis13:45 Breast cancer is the most common form of cancer in women. According to the World Health Organization, in 2022, around 2.3 million women were diagnosed with breast cancer, and the disease caused about 670,000 deaths worldwide. |
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