THE MEDICAL NEWS

Global disease burden is shifting toward aging-related conditions as people live longer, with these diseases now representing the largest expected lifetime health burden for newborns across all income groups. Modeling suggests that reducing aging-related disease could produce unusually large and progressively greater gains in both longevity and healthy life expectancy because improvements in surv…

Late-life semaglutide treatment slowed age-related physiological decline, attenuated multiple molecular hallmarks of aging, and extended median lifespan from 742 to 834 days in aged female mice. The drug reproduced many effects of calorie restriction while providing additional benefits in exploratory behavior, spatial memory, and glucose control, suggesting that some effects extend beyond reduced…

A targeted perspective synthesizes epidemiological and mechanistic evidence examining how caffeine consumption during midlife may influence dementia risk later in life. The authors highlight potential roles for dose, age, CYP1A2 genotype, adenosine signaling and cultural drinking practices, while stressing that current observational evidence cannot establish causality.

In a randomized crossover study of 22 healthy, normal-weight Chinese men, consuming canola oil alone or with spinach before a high-glycemic mashed-potato meal produced flatter post-meal glucose and insulin responses than spinach alone or no preload. The effects were associated with increased GLP-1 signaling and slower gastric emptying, with the findings indicating that the unsaturated oil was the…

The Sussex 4-Day Week study is a 14-week UK protocol designed to investigate how reduced working hours affect physical and mental health, wellbeing, sleep, work performance, and potential biological and psychological mechanisms. Researchers aim to combine questionnaires with actigraphy, inflammatory biomarkers, interoception testing, and brain imaging in at least 150 adults, with data collection …

The American College of Cardiology (ACC) Quality Summit 2026 will take place on September 16-18 in Orlando, connecting the cardiovascular quality improvement community to share ideas, learn from real-world successes and drive measurable improvements in the quality, safety and value of patient care.

When a patient has their DNA read, it gets compared against a reference version of the human genome. It allows geneticists and rare disease experts to look at a list of places where the patient's DNA differs.

New research reveals a promising new target for treating cancer by harnessing a type of molecule previously thought to do more harm than good.

Aging does not appear to follow the same molecular script for everyone, according to an eight-year study of 335 women.

Researchers at the University of Oulu have identified alpha-1 antitrypsin as a potential target for preventing spontaneous preterm birth.