THE MEDICAL NEWS |
Popis: from News-Medical.Net - Latest Medical News and Research from Around the World
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Mailed DNA-based test for colorectal cancer screening10:52 The use of mailed FIT-DNA kits in community health centers significantly increases colorectal cancer screening, though follow-up colonoscopy rates remain low. Baby teeth show when metal exposure may affect brain development10:20 The study identifies critical windows of metal exposure via baby teeth, revealing impacts on brain development and behavior in children and adolescents. Sapio Sciences brings Claude Cowork to the lab8:12 Sapio Sciences, the AI lab informatics company, today announced that Claude Cowork, Anthropic's agentic AI assistant, is now integrated with the Sapio Platform via Sapio Elain, the AI co-scientist. DeNovix launches Squid™ Full Range Pipette: A single device covering 1 – 1000 µL7:40 DeNovix Inc. has introduced a new product to their innovative collection of life science devices—the Squid™ Full Range Pipette. From killers to strategists: CAR T cells enter their multifunctional era7:40 A review of 1,801 registered CAR T clinical trials shows that multifunctional designs now account for 533 trials and 33% of new CAR T products submitted for clinical testing in 2025. The field is shifting toward multitargeted, safety-controlled, cytokine-secreting, and checkpoint-modulating CAR T cells, but manufacturing, regulation, and limited clinical outcome data remain key barriers. Single-cell sequencing reveals why some CAR-T therapies succeed while others fail6:36 Single-cell RNA sequencing is giving researchers a clearer view of why some CAR-T cells persist, expand, kill tumors effectively, or become exhausted. The review synthesizes 44 clinical scRNA-seq studies involving 500 patients and highlights how exhaustion, memory, cytotoxicity, clonal diversity, and metabolism may shape CAR-T responses. Metabolic rewiring could help CAR-T cells fight solid tumors5:32 This review explains how glucose scarcity, lipid disruption, amino acid deprivation, and toxic metabolites weaken CAR-T cells inside solid tumors. It highlights metabolic reprogramming as a promising strategy to improve CAR-T cell persistence, adaptability, and anti-tumor function. New brain stimulation technique improves social communication in children with autism5:32 A new non-invasive brain stimulation technique known as accelerated continuous theta burst stimulation (a-cTBS) improves social communication at one month follow up and has a favorable safety profile in children with autism, finds a trial from China published by The BMJ today. How multi-omics is changing what scientists can see in the human immune system5:01 Human systems immunology is using multi-omics, single-cell tools, spatial technologies, and AI to decode immune responses across real-world human cohorts. The review highlights major opportunities for biomarker discovery and precision medicine, while stressing the need for rigorous study design, validation, and careful interpretation. New imaging agent shows promise for non-invasive endometriosis diagnosis5:01 The Nuffield Department of Women's & Reproductive Health at the University of Oxford, together with Serac Healthcare Limited announces the publication of Phase 2 data in The Lancet Obstetrics and Gynaecology. |