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Functional angiography outperforms conventional imaging in AIR-STEMI trial21:10 Functional coronary angiography significantly reduced cardiovascular events and improved safety compared with conventional angiography in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease. Digital registry strategy doubles heart failure treatment uptake21:10 A registry-based digital strategy that identified untreated patients and invited them to a telephone consultation more than doubled implementation of an effective type of heart failure treatment. FDA approves daraxonrasib for patients with metastatic pancreatic cancer21:10 The U.S. Food and Drug Administration (FDA) has approved daraxonrasib for patients whose pancreatic cancer has spread to other parts of the body and continued to progress despite previous treatment. SWITCH SWEDEHEART trial shows prasugrel matches ticagrelor with less bleeding20:38 Prasugrel reduced major cardiovascular events to the same extent as ticagrelor but with lower major bleeding after coronary stenting in patients with acute coronary syndromes, according to results from the SWITCH SWEDEHEART trial presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine. Trial shows antiplatelet therapy needs personalization after stent implantation20:38 Antiplatelet monotherapy reduced bleeding but dual therapy provided greater cardiovascular event protection in patients at high ischemic risk who had undergone stent implantation 12 months earlier. Milvexian fails to reduce cardiovascular events after acute coronary syndrome20:38 Milvexian did not reduce major adverse cardiovascular events compared with placebo after a recent acute coronary syndrome and there was no increase in intracranial or fatal bleeding. Trial findings do not support prasugrel monotherapy at the time of primary PCI for STEMI patients20:38 Monotherapy using prasugrel failed to show noninferiority compared with potent antiplatelet therapy plus aspirin at the time of primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. Potent antiplatelet therapy increases bleeding risk after heart attack in AF patients20:38 Potent antiplatelet therapy increased bleeding without signs of benefit regarding cardiovascular events in patients with atrial fibrillation after a heart attack. Atorvastatin reduces major cardiovascular events but misses disability-free survival goal20:06 Atorvastatin reduced major cardiovascular events by 30% in older people without known cardiovascular disease, diabetes or dementia, but did not significantly improve disability-free survival, according to results presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine. REACT study maps widespread silent atherosclerosis across adult lifespan20:06 Silent atherosclerosis was detectable from early adulthood and showed sex-specific patterns of growth with age, according to results from the REACT study presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine. |
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