THE MEDICAL NEWS

Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and environmental exposures shape the human immune system through distinct DNA methylation mechanisms. Genetic effects concentrate within gene bodies of memory cells, while environmental exposures primarily remodel regulatory regions in naive immune cells.

This cross-sectional study of 300 school-aged girls in Tehran found that higher air pollution exposure was consistently associated with poorer concentration, while dietary antioxidant capacity showed weaker, model-dependent links to attention. No significant associations or interactions were observed for short-term memory, highlighting pollution exposure as the dominant factor influencing attenti…

Researchers modelled future injury risk in male professional footballers across seven European leagues and linked this risk to market valuation using a two-stage econometric approach. A higher predicted probability of severe or recurrent injury was associated with a substantial reduction in players’ market value.

Lifetime alcohol intake, not just recent drinking, is associated with colorectal cancer risk in older adults followed in the PLCO Cancer Screening Trial. Heavy and consistent long-term drinking was linked to higher colorectal cancer risk, while alcohol cessation was associated with lower odds of early, nonadvanced adenomas.

UVA Health scientists are reporting promising success as they pioneer a new way to create vaccines far more quickly, nimbly and inexpensively than ever before.

Doctors may soon be able to tell just how sick a heart failure patient really is by using a routine MRI scan, thanks to new research from the University of East Anglia.

The tiny zebrafish is helping researchers rapidly determine whether a newborn's genetic mutation is likely to cause spinal muscular atrophy (SMA), one of the leading causes of infant mortality worldwide.

More than 135 million American adults are either living with or at risk for type 2 diabetes (T2D), elevating the need for more evidence-based dietary guidance to help this growing population achieve optimal health and reduce risks for T2D and its complications.

Targeted protein degradation presents a promising strategy to address antimicrobial resistance, focusing on innovative approaches for gram-negative bacteria.