THE MEDICAL NEWS |
Popis: from News-Medical.Net - Latest Medical News and Research from Around the World
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Vulnerable DNA sites make cancer cells sensitive to PARP inhibitors18:09 A small subset of vulnerable DNA sites can make cancer cells highly sensitive to targeted drugs called PARP inhibitors, a new study shows. Automated text messages improve bowel cancer screening in London18:09 As low-cost and straightforward an intervention as automated text messaging could make a significant contribution to tackling London's below-average bowel cancer screening rates, according to a major study led by the University of Surrey. Compound YZG-331 leverages gut microbiota to improve sleep in mouse models of insomnia16:01 This new article publication from Acta Pharmaceutica Sinica B discusses how interactions between the investigational compound YZG-331 and the gut microbiota contribute to its sleep-promoting effects in mouse models of insomnia. Anti-PEG antibodies drive contrasting liposome skin toxicity across species15:29 This new article publication from Acta Pharmaceutica Sinica B discusses how anti-polyethylene glycol antibodies affect the movement of stealth liposomes from blood into skin, revealing contrasting distribution and toxicity patterns in mice and rats. Pattern-based patient selection associated with positive clinical trial results15:29 This new article publication from Acta Pharmaceutica Sinica B discusses the association between using traditional Chinese medicine patterns to select participants and statistically significant primary outcomes in randomized placebo-controlled trials of Chinese herbal formulas. Review explores intrinsic mechanisms driving right ventricular remodeling in pulmonary arterial hypertension15:29 Announcing a new article publication for Cardiovascular Innovations and Applications. Pulmonary arterial hypertension (PAH) comprises a group of progressive pulmonary circulatory diseases characterized by a persistent increase in pulmonary vascular resistance. New covalent inhibitor targets DNAJC9 to reduce sepsis inflammation15:29 This new article publication from Acta Pharmaceutica Sinica B discusses the discovery of the covalent inhibitor A12 and the identification of DNAJC9 as a potential drug target for sepsis-associated inflammation. Innovative framework advances EEG-based emotion recognition15:29 Emotion recognition plays an important role in understanding human cognition and behavior, and has potential applications in brain-computer interfaces and mental health monitoring. Delivering integrated HIV and substance use services through mobile units could save lives15:29 Results from a clinical trial funded by the National Institutes of Health (NIH) in five major United States cities show that delivering integrated HIV and substance use disorder (SUD) services using peer navigation in mobile medical units reduced all-cause deaths by 71% compared to participants who received peer navigation to community-based services alone. Topadur’s Phase 2a trial of TOP-N53 for systemic sclerosis-associated digital ulcers advances to next dose levels13:52 Topadur Pharma AG, a Swiss clinical-stage biopharmaceutical company, today announced that the Safety Review Committee of its Phase 2a trial has recommended progression to the next planned dose levels. |