THE MEDICAL NEWS |
Popis: from News-Medical.Net - Latest Medical News and Research from Around the World
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CRISPR-Cas orchestrates a layered defense network to fight bacterial viruses15:29 All cellular life-from humans to bacteria-possesses two layers of immunity: innate and adaptive. Scientists have long understood how these two types of immunity work together in higher organisms but not in the microbial world. Compact genetic switch enables targeted gene therapy for epilepsy15:29 Epilepsy affects over 50 million people worldwide, making it one of the most common neurological disorders. Study reveals unexpected mechanism driving extreme antibiotic resistance14:57 A patient with a severe infection is prescribed a potent antibiotic. Hopes for improvement are high, but just after treatment is given, resistance to the drug increases thousands of times. How could this happen? New bacterial control strategy helps revive failing last-line antibiotics14:25 Antimicrobial resistance is one of the world's most alarming public health challenges, because the multidrug-resistant (MDR) gram-negative bacteria increasingly render even last-line antibiotics ineffective, leading to substantially higher mortality rates. AI-powered analytics and experimental validation: Transforming target identification in drug discovery13:54 Discover how AI-powered analytics and experimental validation combine to improve target identification and accelerate drug discovery success. Short-term immunosuppressive therapy briefly restores autism-like brain changes in adult mice13:53 A new mouse study led by UCLA Health suggests that inflammation during pregnancy can trigger autism-like changes in offspring, but also that those brain and behavior effects may be rapidly but temporarily reversible in adulthood with a short-term dose of the immunosuppressive drug rapamycin. Emerging PPAR therapies offer new hope for primary biliary cholangitis13:53 Primary biliary cholangitis is a rare autoimmune disease that affects the liver and can progress to cirrhosis. It occurs when the immune system attacks the small bile ducts within the liver. As a result, bile builds up, leading to inflammation and progressive liver damage. Although a first-line treatment exists, 40% of patients do not respond adequately to it or cannot tolerate it, so new treatme… Dormant melanocytes found in vitiligo offer hope for future repigmentation therapies13:21 Vitiligo is an autoimmune disease in which the body's immune system attacks and destroys melanocytes, the cells that produce the skin pigment melanin. Once the melanocytes are gone, the skin turns white, leading to the characteristic skin patches of the disease. Study reveals regional disparities in Brazilian childhood leukemia mortality13:21 An international study involving LMU found regional differences in childhood lymphoid leukemia mortality across Brazil. |