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Researchers rank 11 preeclampsia therapies as top candidates for further development3:35 Researchers ranked 83 preclinical candidates for preventing or treating preeclampsia and eclampsia, identifying 11 as having high potential for further development. The analysis also revealed limited target diversity, moderate bias, inactive programs, and animal models that may not fully represent human pregnancy Scientists develop ultrathin skin sensors for seamless health tracking22:18 While wearable health sensors are becoming increasingly common, current iterations are awkward to wear. New drug candidate improves Parkinson's treatment in animal models22:18 For many people with Parkinson's disease, the body stops moving the way it used to. A hand may tremble at rest. Muscles may stiffen. Framing loneliness as a medical issue hinders societal responsibility22:18 While loneliness has been shown to harm one's health, framing it as a health issue shifts responsibility from society to healthcare, even though healthcare alone cannot rebuild social ties, a new University of Michigan study warns. Brain’s immune cells play key role in maintaining stability of neuronal networks in Alzheimer's disease21:46 Researchers at Trinity College Dublin have discovered that microglia – the main immune cells of the brain – play a critical role in maintaining the stability of neuronal networks in Alzheimer's disease. AI model predicts effective immunotherapy combinations for liver cancer21:46 Using computational tools, researchers from the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a method to predict which patients with a primary liver cancer called hepatocellular carcinoma (HCC) would most benefit from combination treatment using immunotherapy and a targeted therapy that blocks the growth signals that the tumor depends on. Self-assembling antibody drugs successfully target multiple cancer receptors21:46 Modern anticancer medications that combine tumor-fighting drugs with proteins that specifically target cancer cells are a relatively new class of drug, often given to patients for whom standard chemotherapy has not worked. New machine learning model improves cholesterol calculation accessibility21:46 The Martin-Hopkins equation to assess low-density lipoprotein (LDL) cholesterol levels in blood samples has been used by laboratories in the U.S. and other countries to guide efforts to lower cardiovascular disease risk. Ketogenic diet may increase small intestine cancer risk in mice21:14 A high-fat, low-carbohydrate diet, also called a ketogenic diet, can help some people lose weight by forcing their bodies to burn fat for fuel instead of sugar. Low-nicotine cigarettes do not cause increased compensatory smoking21:14 People who switch to cigarettes with dramatically reduced nicotine levels are unlikely to smoke more cigarettes or inhale more smoke to compensate for the lower nicotine content, according to a new study led by researchers at Wake Forest University School of Medicine and published in JAMA Network Open. |
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