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THE MEDICAL NEWS

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from News-Medical.Net - Latest Medical News and Research from Around the World

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Life & Style → Health

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Tizanidine looked promising early in a migraine trial, but the benefit did not last

7:03
A randomized, double-blind, placebo-controlled trial found that low-dose tizanidine did not provide sustained reductions in headache burden over 12 weeks in people with episodic migraine, despite a transient improvement with the 1 mg dose at week 4. Exploratory analyses suggested that smoking and sex may influence tizanidine exposure, while sex-specific efficacy signals remained hypothesis-genera…

Rentosertib shifts multiple proteomic aging clocks toward younger age profiles in IPF trial

6:32
Researchers applied six proteomic aging clocks to serum samples from a phase 2a trial of rentosertib in people with idiopathic pulmonary fibrosis and found treatment-associated shifts toward younger predicted biological-age profiles, particularly with the 30 mg twice-daily regimen. Additional proteomic analyses linked treatment to changes in senescence, metabolism, growth-factor signaling, and fi…

Bruker advances whole-organism 3D imaging with enhanced tissue-clearing workflows

6:32
Bruker Corporation today announced a strategic collaboration with Translucence Biosystems, Inc., a leading provider of tissue‑clearing solutions, to expand its workflow for cleared tissue imaging.

Yourgene Health launches Insight DPYD assay (IVDR)

6:31
Yourgene Health (part of the Novacyt Group), an international molecular diagnostics company with a broad portfolio of integrated technologies and services, announces the commercial launch of its In Vitro Diagnostic Regulation (IVDR)-certified Yourgene® Insight DPYD assay, expanding the Company's clinical genetics portfolio across regulated European markets.

Gut microbiome may reveal inflammation and future disease risk better than age

5:59
Gut microbiota composition explained more variation than chronological age in nearly all inflammatory cytokines and most physiological measures examined, with specific microbial profiles linked to markedly different patterns of inflammation across adulthood. People with the Bacteroides 2 enterotype showed an inflammaging-like profile decades earlier than other groups and had a higher risk of subs…

Minimum waits delay patient care across England, BMJ data reveals

5:59
Nearly half of health boards in England are deliberately delaying care for patients by imposing minimum waiting times in an attempt to manage demand and control costs, reveals exclusive data published by The BMJ today.

Dementia prevention should look beyond individual choices, study finds

5:59
Efforts to prevent dementia may be placing too much responsibility on people's choices while overlooking the wider social and environmental conditions that shape brain health, according to new Curtin University research published in The Lancet Public Health.

Blood protein profiling could improve rare disease diagnosis

5:59
Researchers from Queen Mary University of London, the Berlin Institute of Health at Charité (BIH) and Genomics England have shown that measuring proteins in the blood can provide important additional clues about the effects of genetic variants, helping to identify diagnoses and potential new disease-causing genes that genome sequencing alone has been unable to resolve.

Why researchers are looking at psilocybin for repeated mild head injuries

5:59
In female rats with repetitive mild head injury, psilocybin reduced acute imaging measures consistent with vasogenic edema and phosphorylated tau while altering vascular reactivity, functional connectivity, neurotrophic proteins, and lipid signaling. The findings provide preclinical evidence of potential therapeutic effects, but behavioral benefits were limited, and whether these biological chang…

Spleen imaging features may reveal coronary artery disease risk

5:28
A new study led by investigators from Mass General Brigham reveals that certain features in the spleen hidden within imaging scans may signal a person's risk of coronary artery disease (CAD), suggesting targets for prevention and treatment.
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