THE MEDICAL NEWS |
Popis: from News-Medical.Net - Latest Medical News and Research from Around the World
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Insilico and SK Biopharmaceuticals partner to develop AI-driven neuroimmune therapies5:17 Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, and SK Biopharmaceuticals, a Korean-based company leads the way in biotech innovation with groundbreaking drug research, development, and commercialization worldwide, announced a research and development collaboration at the BIO 2026 International Convention to discover AI-enabled innovative… Accelerated biological aging may drive rising early-onset cancer risk5:17 Cancer is often considered a disease of aging. Older adults are at higher risk because they have had more time to accumulate cellular damage that can trigger tumor formation. New AI platform tracks cancer treatment responses in tumor organoids5:17 Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have developed a new platform that combines 3D bioprinting, advanced imaging and artificial intelligence to better monitor how cancer responds to treatment. Hyperemesis gravidarum increases risks for pregnancy and birth complications5:17 Pregnant women with a severe form of nausea face increased risks for several pregnancy and birth complications, according to a new Stanford Medicine study of 2.5 million California births. Novel IL1RAP therapy advances toward pancreatic cancer clinical trial5:17 Blocking IL1RAP, a receptor that sits at a key control point in inflammatory signaling, can disrupt the tumor-driven inflammatory network that helps pancreatic cancer resist treatment, according to new research. Psychological traits may uncover why Alzheimer’s biology differs between patients4:09 In 822 deceased older adults from ROS and MAP, researchers linked stable psychological traits to multi-omic molecular subtypes of Alzheimer’s dementia using postmortem brain tissue from the dorsolateral prefrontal cortex. Neuroticism and loneliness were associated with molecular progression, while purpose in life showed subtype-specific inverse associations, suggesting psychological traits may al… Amazon land use patterns reveal where vector-borne diseases collide4:08 Researchers found that malaria-Chagas and dengue-ATL hotspots in the Brazilian Amazon aligned with distinct agrarian, socioeconomic, and environmental landscapes. The findings suggest that disease surveillance should account for land use, poverty, forest structure, mining, and local livelihoods rather than treating each infection in isolation. Statins may trigger muscle side effects by activating inflammatory danger signals3:35 An experimental study in Science Advances shows that statins, primarily fluvastatin in these experiments, may promote low-level muscle myopathy by reducing isoprenoid-dependent protein prenylation rather than by cholesterol lowering. In primed muscle cells and mouse models, impaired YAP signaling, reduced glycolysis, NLRP3/caspase-1 activation, and nuclear FOXO accumulation increased atrogin-1, r… Scientists trace cardiac aging to a fading regulator in heart muscle cells3:03 Researchers mapped 442,239 single nuclei from nonfailing human hearts to chart how cardiac cells change from fetal development to older adulthood. The study identified PRDM16 as an age-declining cardiomyocyte regulator, with experimental evidence showing that restoring Prdm16 in aged mouse hearts improved systolic function and partly reversed aging-associated transcriptional patterns. Using the mathematics of quantum mechanics to improve neuroblastoma outcomes22:36 For a child diagnosed with neuroblastoma-the most common infant cancer, occurring when early nerve cells grow out of control-the path to treatment isn't simple. |