THE MEDICAL NEWS

Women who reach menopause before age 40 face a meaningfully higher risk of developing high blood pressure than those who go through menopause after age 45, according to a new study of more than 107,000 women.

Nearly 23 million Americans with blood pressure 130/80 mm Hg or higher may be eligible for blood-pressure-lowering medications based on the 2025 American Heart Association/American College of Cardiology guideline, according to new, independent research published today in the Journal of the American Heart Association, an open access, peer-reviewed scientific journal of the American Heart Associati…

Researchers compared beliefs from 887 US adults with modeled lifespan trajectories from 166,971 participants across eight longitudinal studies. Population-average Big Five traits changed as much as or more than many health, financial, psychological, and social measures, despite people perceiving personality as unusually stable.

Researchers found that regular meals, Mediterranean diet adherence, sufficient sleep, and limited television viewing were independently associated with better grades among 974 adolescents. Meeting more healthy lifestyle recommendations was consistently associated with stronger performance across first, second, and third languages.

Researchers used single-molecule and super-resolution imaging to profile protein aggregates across six brain regions from 29 post-mortem donors, detecting high-intensity phosphorylated tau aggregates in the Parkinson’s disease putamen despite negligible conventional tau staining. PD cases with dementia showed greater tau burden than those without dementia, while the assay did not detect a PD-spec…

Researchers developed Oncoformer, a multimodal transformer that analyzes longitudinal health records and chest X-rays to classify cancer, predict diagnoses up to one year in advance, infer tumor stage, and forecast treatment response and recurrence risk. Validation across large independent cohorts showed strong performance, although prospective trials in diverse, average-risk populations are need…

In many animal tissues, stem cells continually divide to create new cells that replace old or damaged ones. However, this capacity requires strict regulation, as uncontrolled stem cell proliferation can disrupt tissue homeostasis and contribute to tumorigenesis.