THE MEDICAL NEWS

Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal mortality worldwide. In addition, HDP can lead to fetal growth restriction, preterm birth, and various long-term adverse health outcomes.

New data analyzing more than 20,000 patients from three major NIH studies show that elevated Lipoprotein(a) [Lp(a)] is associated with residual cardiovascular risk and warrants aggressive risk reduction.

Results from a new analysis show that patients with mitral annular calcification (MAC) who undergo minimally invasive mitral transcatheter edge-to-edge repair (M-TEER) experience similar reductions in mitral regurgitation (MR) and improvement in quality of life compared to those seen in patients without calcification.

Findings from the North American COVID-19 Myocardial Infarction (NACMI) registry demonstrate significantly higher one-year mortality rates in patients with COVID-19 and ST-elevation myocardial infarction (STEMI) compared to patients with STEMI alone.

A multi-center retrospective cohort study examined how cangrelor has been used in real-world clinical practice around the time of surgery following percutaneous coronary intervention (PCI) and described differences in outcomes seen with different dosing approaches.

The first comparative analysis from the ENGULF (A Safety and Feasibility Single-Arm Study of a Novel Catheter Thrombectomy Device For the Treatment of Pulmonary Embolism) trial shows that using blood return during continuous aspiration thrombectomy dramatically reduces blood loss by 97%, while maintaining hemodynamic efficacy and improving procedural efficiency.

A new set of drugs exploit a recently-revealed weakness in 'zombie-like' – or senescent – cells that could lead to new treatments for cancer and age-associated diseases.

Tenofovir alafenamide (TAF) has demonstrated comparable efficacy to tenofovir disoproxil fumarate (TDF), with improved renal and bone safety, in Chinese participants with chronic hepatitis B enrolled in two Phase 3 trials.