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Maxillary nerve block may reduce perioperative opioid consumption in pediatric primary clefts17:42 For infants undergoing cleft palate surgery, local anesthetic injection targeting the maxillary nerve of the face may reduce or eliminate the need for opioid medications to control postoperative pain, reports a study in The Journal of Craniofacial Surgery. Mass General Brigham launches AI company to enhance clinical trial matching17:42 Mass General Brigham is announcing the spinout of AIwithCare, a company founded by researchers from the health system who developed an artificial intelligence (AI) screening tool that significantly outperformed manual screening for determining a patient's eligibility and enrolling them in a clinical trial. Acupuncture improves breast cancer survivors' perceived cognitive impairment15:28 Real and sham acupuncture were more effective at improving breast cancer survivors' perceived cognitive impairment compared with usual care, while real acupuncture was superior to sham acupuncture in improving objective cognitive function, according to results from the randomized ENHANCE phase II clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025. Menopausal hormone therapy shows no added breast cancer risk for BRCA carriers15:28 Using menopausal hormone therapy (MHT) was not associated with an increased risk of breast cancer in women with inherited mutations in the BRCA1 or BRCA2 genes, according to the results of a matched prospective analysis presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025. Mobile health intervention improves quality of life for adolescent and young adult breast cancer survivors15:28 A mobile health (mHealth) intervention for adolescent and young adult breast cancer survivors that offered tailored support by monitoring electronic patient-reported outcomes (ePROs) significantly improved quality of life and symptoms related to vaginal and arm problems, according to results from a randomized clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held Decemb… Researchers identify chromatin accessibility changes driving stem cell transformation in MDS14:56 Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and differentiation sustains healthy blood formation. Most clinical trials fail to reflect America’s racial and ethnic diversity14:56 A new study finds just 6% of clinical trials used to approve new drugs in the U.S. reflect the country's racial and ethnic makeup, with an increasing trend of trials underrepresenting Black and Hispanic individuals. Plant-based diets support healthy growth when properly planned for children14:24 Vegetarian and vegan diets can support healthy growth when carefully planned with appropriate supplementation, finds a major new meta-analysis – the most comprehensive study to-date of plant-based diets in children. Increased epicardial fat volume linked to greater myocardial injury after infarction14:24 Increased volume of epicardial adipose tissue, detected by cardiovascular imaging, was found to be associated with greater myocardial injury after a myocardial infarction. Fear strongly influences pain perception in inflammatory bowel disease patients14:24 Pain perception in affected individuals is more strongly influenced by learned fear than in healthy individuals. Changes along the gut-brain axis related to chronic inflammation may explain this. |
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