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Popis: from News-Medical.Net - Latest Medical News and Research from Around the World
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Orexo and SVF Vaccines collaborate to explore AmorphOX® formulation of LNP-mRNA vaccines9:14 Orexo AB and SVF Vaccines AB today announced a research collaboration to investigate whether Orexo’s proprietary powder-based drug delivery technology, AmorphOX®, can be used to develop stable powder-based formulations of lipid nanoparticle (LNP)-encapsulated messenger RNA (mRNA) vaccines. Richmond Pharmacology highlights encouraging first-in-human results for Regeneron's investigational RNAi therapy in MASLD8:10 Richmond Pharmacology, a specialist early-phase clinical research organization, has announced encouraging results from a first-in-human clinical trial evaluating CIDEBsiRNA, an investigational RNA interference (RNAi) therapy developed by Regeneron Pharmaceuticals, Inc. Researchers associate personality shifts with frontotemporal dementia functional decline8:10 Frontotemporal dementia often results in early changes in personality or behavior before changes in cognitive skills. Ephrin-B1 phosphorylation disrupts nephrin complexes in nephrotic syndrome pathogenesis7:38 A group led by the Department of Cell Biology at the Kidney Research Center, Niigata University identified a novel Ca2+-independent pathogenic mechanism of nephrotic syndrome. Beyond food: Bran-based gels show potential for targeted drug delivery7:06 When it comes to colon health, the benefits of wheat and rye bran in wholegrain foods are well-known. Now researchers in Sweden have shown how these fibers may have a therapeutic use, too. Adelaide researchers investigate optimal exercise and education for neck pain7:06 Whether you hunch over a computer or spend hours scrolling on your phone, everyday habits can be a real pain in the neck. But when that pain persists, it can take a serious toll on everyday life, affecting everything from work and sleep to physical activity and wellbeing. Study decodes combinatorial p53 modification networks7:06 A recent review highlights that p53 activity is orchestrated by a combinatorial network of post-translational modifications (PTMs), in which writers, erasers and reader proteins dynamically shape protein stability, DNA binding, subcellular localization, co-regulator assembly and transcriptional output. Meta analysis quantifies annual Alzheimer's incidence in type 2 diabetes7:06 A Curtin University-led review has revealed type 2 diabetes significantly raises risk of developing Alzheimer's disease. Yale Cancer Center offers team-based care for breast cancer patients6:34 Hilary Axtmayer can pinpoint the moment her life changed. In 2023, Axtmayer-then a 40-year-old mother of two from Madison, Conn.-was receiving her regularly scheduled breast exam when her gynecologist paused mid-palpation. She'd found a lump. New method reveals how individual glioblastoma cells spread through the brain6:34 By combining live imaging of brain tissue with artificial intelligence, researchers at Uppsala University have developed a method that reveals how individual glioblastoma cells spread through the brain, how they can switch between different ways of moving, and how they are affected by cancer treatments. An |