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Short-term oatmeal diet improves cholesterol and metabolic health markers6:23 A short-term oat-based diet appears to be surprisingly effective at reducing the cholesterol level. This is indicated by a trial by the University of Bonn, which has now been published in the journal Nature Communications. AI-designed NLRP3 inhibitor receives FDA clearance for Parkinson disease trials5:51 Insilico Medicine (3696.HK), a clinical-stage drug discovery and development company driven by generative artificial intelligence (AI), today announced that ISM8969, an orally available NLRP3 inhibitor targeting inflammation and neurodegenerative disorders, has recently received investigational new drug (IND) clearance from the U.S. Food and Drug Administration (FDA), intended for the treatment o… Structured assessment framework aims to ensure safe, ethical deployment of clinical LLMs5:51 A new expert consensus made available online on 10 October 2025 and published in Volume 5, Issue 4 of the journal Intelligent Medicine on 1 November 2025, sets out a structured framework to assess large language models (LLMs) before they are introduced into clinical workflows. Evidence of African lineage Zika virus circulation in neotropical primates in Southern Brazil5:51 Announcing a new article publication for Zoonoses journal. Mosquito-borne orthoflaviviruses are maintained in cycles involving mosquito and vertebrate hosts. Ultra-thin nanotechnology enables safe wireless stimulation for retinal degeneration5:51 An international research team led by Prof. Dr. Sedat Nizamoğlu from the Department of Electrical and Electronics Engineering at Koç University has developed a next-generation, safe, and wireless stimulation technology for retinal degenerative diseases that cause vision loss. MYC cancer gene suppresses immune alarm signals to protect pancreatic tumors5:20 The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system. Camera-based technology measures cardiopulmonary coupling without physical sensors5:20 From a physiological perspective, heartbeats and breathing do not operate independently in the human body. Cardiac rhythm varies with the respiratory cycle, and the close interaction between the two is known as cardiopulmonary coupling (CPC). Resurrected ancient enzyme reveals early life processes and astrobiological biosignatures5:20 By resurrecting a 3.2-billion-year-old enzyme and studying it inside living microbes, researchers at the University of Wisconsin–Madison have created a new way to improve our understanding of the origins of life on Earth and possibly recognize signs of life elsewhere. Bacterial infections in patients with liver cirrhosis show rising prevalence and high mortality3:45 Bacterial infections (BIs) are common and severe complications in patients with liver cirrhosis, but global data are limited. Here, we aimed to evaluate the global prevalence, temporal changes, and associated mortality risk of BIs in liver cirrhosis. Cigarette compound exposure drives sorafenib resistance in hepatocellular carcinoma3:45 A research team led by Professor Yuan Li at Nanjing Medical University published a research paper entitled "A Cigarette Compound-Induced Tumor Microenvironment Promotes Sorafenib Resistance in Hepatocellular Carcinoma via the 14-3-3η-Modified Tumor-Associated Proteome" in the Chinese Medical Journal. |