ScienceDaily

A newly discovered molecule could reshape the future of weight loss treatments by mimicking the powerful appetite-suppressing effects of drugs like Ozempic — but without many of the unpleasant side effects. Identified using artificial intelligence, this tiny peptide, called BRP, appears to act directly on the brain’s appetite-control center, helping animals eat less and lose fat without nausea or…

For years, scientists believed our lifespan was mostly shaped by environment and chance, with genetics playing only a minor role. But a new study from the Weizmann Institute flips that idea on its head, revealing that genes may actually account for about half of the differences in how long people live. By analyzing massive twin datasets—including twins raised apart—and using innovative simulation…

A colossal “cosmic volcano” has erupted in deep space, as a supermassive black hole in galaxy J1007+3540 roars back to life after nearly 100 million years of silence. Astronomers captured stunning radio images showing fresh jets blasting outward while crashing into the intense pressure of a surrounding galaxy cluster, creating a chaotic, distorted structure stretching nearly a million light-years.

A twice-yearly injection may soon change how high blood pressure is treated. In a global trial, patients receiving the experimental drug zilebesiran alongside standard therapy saw greater blood pressure reductions than those on standard treatment alone. The drug works by blocking a key liver protein, helping blood vessels relax. Researchers say this long-lasting approach could make it much easier…

The first-ever published research on Tinshemet Cave reveals that Neanderthals and Homo sapiens in the mid-Middle Paleolithic Levant not only coexisted but actively interacted, sharing technology, lifestyles, and burial customs. These interactions fostered cultural exchange, social complexity, and behavioral innovations, such as formal burial practices and the symbolic use of ochre for decoration.…

A cave in Belgium has revealed unsettling evidence that Neandertals selectively cannibalized outsiders, focusing on women and children. The victims weren’t from the local group and appear to have been treated like prey, with bones butchered for meat and marrow. This suggests the behavior wasn’t ritual, but practical—or possibly linked to intergroup conflict. The discovery paints a darker, more co…

Researchers are launching a new project to crack the mystery of aggressive breast cancer, where predicting disease progression remains a major hurdle. By studying how tumors interact with and suppress the immune system, scientists aim to identify new biomarkers that reveal how the cancer evolves. Using real patient samples, the team hopes to turn earlier discoveries into practical clinical tools.…

A new study reveals that popular diabetes and weight-loss drugs like Ozempic and Wegovy may not work as effectively for about 10% of people due to specific genetic variants. These individuals appear to have a puzzling condition called “GLP-1 resistance,” where their bodies produce higher levels of the hormone targeted by these drugs—but don’t respond to it properly.

A new nanodisc-based platform lets scientists study viral proteins in a form that closely mimics real viruses, revealing how antibodies truly recognize them. This approach uncovered hidden interactions in viruses like HIV and Ebola that traditional methods missed. By recreating the virus’s membrane environment, researchers can better understand how immune defenses work. The technique could speed …

Mars may be hostile, but it might not be entirely unlivable. In lab experiments, yeast cells survived simulated Martian shock waves and toxic perchlorate salts—two major environmental threats on the Red Planet. Their secret weapon was forming protective molecular clusters that shield critical cellular functions under stress. Without these defenses, survival plummeted, pointing to a potential univ…

A major international effort has produced an ultra-precise measurement of the Universe’s expansion rate, confirming it’s faster than early-Universe models predict. By linking multiple distance-measuring techniques, scientists ruled out simple errors as the cause of the discrepancy. The persistent “Hubble tension” now looks more real than ever. It could mean our current model of the cosmos is inco…

A major study suggests that when you eat could play a key role in staying lean. People who fast longer overnight and start their day with an early breakfast were more likely to have a lower BMI years later. Scientists think this is because eating earlier aligns better with the body’s internal clock. But skipping breakfast as part of intermittent fasting didn’t offer the same advantage—and may eve…

Scientists searching for air pollution clues stumbled onto something unexpected: toxic MCCPs drifting through the air for the first time in the Western Hemisphere. The likely source—fertilizer made from sewage sludge—points to a hidden route for contamination.

Scientists have achieved the unthinkable by stabilizing a highly reactive molecule in water, confirming a decades-old theory about vitamin B1’s role in the body. The breakthrough not only solves a scientific mystery but could revolutionize greener chemical manufacturing.

Losing your sense of smell might signal Alzheimer’s far earlier than expected. Scientists found that immune cells in the brain actively destroy smell-related nerve fibers after detecting abnormal signals on their surfaces. This damage begins in early stages of the disease, well before cognitive decline. The discovery could help identify at-risk patients sooner and improve treatment timing.