ScienceDaily

Researchers identified SGK1 as a key chemical connecting childhood trauma to depression and suicidal behavior. High SGK1 levels were found in the brains of suicide victims and in people with genetic variants linked to early adversity. Drugs that block SGK1 could offer a new kind of antidepressant, especially for patients resistant to SSRIs.

Scientists have found that keratin, the protein in hair and skin, can repair and protect tooth enamel. The material forms a mineralized layer that halts decay and restores strength, outperforming traditional fluoride. Made from sustainable sources like hair, it could soon be available in toothpaste or gels. The discovery could transform dentistry by turning waste into a powerful tool for regenera…

Researchers have discovered that prostate cancer depends on two key enzymes, PDIA1 and PDIA5, to survive and resist therapy. When blocked, these enzymes cause the androgen receptor to collapse, killing cancer cells and enhancing the effects of drugs like enzalutamide. They also disrupt the cancer’s energy system, striking it on multiple fronts. This breakthrough could open a new path to overcomin…

A sweeping review of existing studies finds no solid evidence that using acetaminophen (Tylenol) during pregnancy increases the risk of autism or ADHD in children. Researchers found that previous reviews often relied on weak or biased data, and most did not properly account for genetic or environmental factors shared by families. When these factors were considered, any apparent link between aceta…

In Peru’s mysterious Pisco Valley, thousands of perfectly aligned holes known as Monte Sierpe have long puzzled scientists. New drone mapping and microbotanical analysis reveal that these holes may once have served as a bustling pre-Inca barter market—later transformed into an accounting system under the Inca Empire.

New research finds that daily coffee drinking may cut AFib risk by nearly 40%, defying decades of medical caution. Scientists discovered that caffeine’s effects on activity, blood pressure, and inflammation could all contribute to a healthier heart rhythm. The DECAF clinical trial’s findings suggest coffee could be not only safe but beneficial for people with A-Fib.

Intermountain Health researchers discovered that customizing vitamin D3 doses for heart attack survivors slashed their risk of another heart attack by 50%. The strategy involved frequent monitoring and dose adjustments to reach ideal vitamin D levels. Traditional studies didn’t track blood levels, missing this critical link.

XRISM’s observations of GX13+1 revealed a slow, fog-like wind instead of the expected high-speed blast, challenging existing models of radiation-driven outflows. The discovery hints that temperature differences in accretion discs may determine how energy shapes the cosmos.

Scientists have discovered that most chronic fatigue patients experience dysfunctional breathing, which may worsen their symptoms. The likely culprit is dysautonomia, a disruption in how the body controls blood vessels and muscles. Breathing retraining, yoga, or biofeedback could help restore proper breathing rhythm and ease fatigue. The findings open a promising new path for managing this long-m…

New research from UBC Okanagan mathematically demonstrates that the universe cannot be simulated. Using Gödel’s incompleteness theorem, scientists found that reality requires “non-algorithmic understanding,” something no computation can replicate. This discovery challenges the simulation hypothesis and reveals that the universe’s foundations exist beyond any algorithmic system.

Scientists have turned to advanced AI to decode the intricate ecosystem of gut bacteria and their chemical signals. Using a Bayesian neural network called VBayesMM, researchers can now identify genuine biological links rather than random correlations. The system has already outperformed traditional models in studies of obesity, sleep disorders, and cancer.

From Cassini’s awe-inspiring flybys to cutting-edge simulations, scientists are decoding the secrets of Enceladus’s geysers. Supercomputer models show the icy moon’s plumes lose less mass than expected, refining our understanding of its mysterious interior. These discoveries could shape future missions that may one day explore its subsurface ocean—and perhaps even detect life below the ice.

A Japanese-led research team has developed AUN, a groundbreaking immune-independent bacterial cancer therapy that uses two harmonized bacteria to destroy tumors even in patients with weakened immune systems. By leveraging the natural synergy between Proteus mirabilis and Rhodopseudomonas palustris, AUN selectively targets cancer cells, reshapes itself within tumors, and avoids harmful side effect…

A new blood pressure calculator built on extensive clinical trial data helps doctors accurately estimate how much each medication will reduce blood pressure. The tool simplifies complex treatment choices and replaces unreliable BP measurements with solid evidence.

A hospital in Thailand created a quick-action dialysis protocol for patients with metformin-associated lactic acidosis, a dangerous reaction to a common diabetes drug. The program sharply reduced deaths and sped up treatment times. Awareness also soared, showing how organized emergency pathways can transform patient outcomes.