ScienceDaily

Rheumatoid arthritis begins years before pain ever appears, and scientists have now mapped the hidden immune battle that unfolds long before symptoms. By studying people with RA-linked antibodies over seven years, researchers discovered sweeping inflammation, malfunctioning immune cells, and even epigenetic reprogramming in cells that had never encountered a threat. These changes show that the bo…

Researchers at Stanford found a way to cure or prevent Type 1 diabetes in mice using a combined blood stem cell and islet cell transplant. The procedure creates a hybrid immune system that stops autoimmune attacks and eliminates the need for immune-suppressing drugs. The method uses tools already common in clinical practice, putting human trials within reach. Scientists think the same strategy co…

Researchers studying Classic Maya cities discovered that urban growth was driven by a blend of climate downturns, conflict, and powerful economies of scale in agriculture. These forces made crowded, costly city life worthwhile for rural farmers. But when conditions improved in the countryside, people abandoned cities for more autonomy and better living environments. The story turns out to be far …

Using a smart computational search, scientists discovered a catalyst ingredient that finally makes tough alkyl ketones behave the way chemists want. The reaction now runs cleanly and reliably, opening the door to faster and easier molecule-building.

Scientists decoded DNA from millennia-old lentils preserved in volcanic rock silos on Gran Canaria. The findings show that today’s Canary Island lentils largely descend from varieties brought from North Africa around the 200s. These crops survived cultural upheavals because they were so well-suited to the islands’ harsh climate. Their long-standing resilience could make them valuable for future a…

Michigan State University astrophysicists are closing in on one of space science’s biggest mysteries: where the galaxy’s most energetic particles come from. Their studies uncovered a pulsar wind nebula behind a mysterious LHAASO signal and set important X-ray constraints on other potential sources.

Researchers developed a powerful new manganese complex that could revolutionize light-driven chemical reactions. It absorbs light extremely efficiently, has a uniquely long excited-state lifetime, and is far easier to synthesize than previous manganese systems. The team confirmed it successfully transfers electrons as intended. This breakthrough could enable large-scale, sustainable photochemical…

Scientists discovered that lowered brain energy signaling in the hippocampus can lead to both depression- and anxiety-like behaviors in mice. Stress reduced ATP, a molecule important for cell energy and communication. Altering a protein called connexin 43, which helps release ATP, caused similar symptoms even without stress. Restoring this protein improved mood-related behavior.

Scientists discovered that more muscle and less hidden abdominal fat are linked to a younger biological brain age. Deep visceral fat appeared to accelerate brain aging, while muscle mass offered a protective effect.

Beneath the waters off Papua New Guinea lies an extraordinary deep-sea environment where scorching hydrothermal vents and cool methane seeps coexist side by side — a pairing never before seen. This unusual chemistry fuels a vibrant oasis teeming with mussels, tube worms, shrimp, and even purple sea cucumbers, many of which may be unknown to science. The rocks themselves shimmer with traces of gol…

Mars’s Coloe Fossae reveals a landscape shaped by ancient ice ages, with deep valleys, cratered terrain, and frozen debris flows preserved from a time when the planet’s climate dramatically shifted.

An immense pocket of hot rock deep beneath the Appalachians may be a wandering relic of the breakup between Greenland and North America 80 million years ago. Researchers suggest this slow-moving “mantle wave” drifted over 1,800 km to reach its current position, gradually reshaping the continent from below and even helping prop up the Appalachian Mountains long after tectonic activity at the surfa…

Rerouted shipping during Red Sea conflicts accidentally created a massive real-world experiment, letting scientists study how new low-sulfur marine fuels affect cloud formation. The sudden surge of ships around the Cape of Good Hope revealed that cleaner fuels dramatically weaken the ability of ship emissions to seed bright, reflective clouds—cutting this cloud-boosting effect by about two-thirds.

Personalized algorithms may quietly sabotage how people learn, nudging them into narrow tunnels of information even when they start with zero prior knowledge. In the study, participants using algorithm-curated clues explored less, absorbed a distorted version of the truth, and became oddly confident in their wrong conclusions. The research suggests that this kind of digital steering doesn’t just …

Researchers studying Yellowstone’s depths discovered that small earthquakes can recharge underground microbial life. The quakes exposed new rock and fluids, creating bursts of chemical energy that microbes can use. Both the water chemistry and the microbial communities shifted dramatically in response. This dynamic may help explain how life survives in deep, dark environments.