ScienceDaily

Researchers uncovered how fatty molecules called ceramides trigger acute kidney injury by damaging the mitochondria that power kidney cells. By altering ceramide metabolism or using a new drug candidate, the team was able to protect mitochondrial function and completely prevent kidney injury in mice.

By reactivating a long-lost gene, researchers were able to lower uric acid levels and stop damaging fat accumulation in human liver models. The breakthrough hints at a future where gout and several metabolic diseases could be prevented at the genetic level.

Hypersonic flight could one day make long-haul travel as quick as a short movie. Researchers are testing how turbulence behaves at extreme speeds, a critical hurdle for designing these aircraft. Their laser-based krypton experiments suggest turbulence at Mach 6 behaves more like slower airflow than expected. The results could simplify hypersonic vehicle design and accelerate progress toward ultra…

Genetic, isotopic, and forensic evidence has conclusively identified the remains of Duke Béla of Macsó and uncovered remarkable details about his life, ancestry, and violent death. The study reveals a young nobleman with Scandinavian-Rurik roots who was killed in a coordinated, emotionally charged attack in 1272.

A massive, well-preserved impact crater has been uncovered in Guangdong, revealing the signature of a powerful meteorite strike during the Holocene. Measuring 900 meters across, it dwarfs other known craters from the same era. Shock-damaged quartz confirms the intense forces involved. Its survival in a high-erosion environment makes it a geological rarity.

Scientists have finally confirmed a powerful coronal mass ejection from another star, using LOFAR radio data paired with XMM-Newton’s X-ray insights. The eruption blasted into space at extraordinary speeds, strong enough to strip atmospheres from close-orbiting worlds. This suggests planets around active red dwarfs may be far less hospitable than hoped.

Laser light can physically distort Janus TMD materials, revealing how their asymmetrical structure amplifies light-driven forces. These effects could power breakthroughs in photonic chips, sensors, and tunable light technologies.

Scientists have decoded the atomic-level secrets behind catalysts that turn propane into propylene. Their algorithms reveal unexpected oxide behavior that stabilizes the catalytic reaction by clustering around defective metal sites. The findings could help streamline industrial chemistry and inspire better catalysts for major processes like methanol synthesis.

Researchers in Greenland used a 10-kilometer fiber-optic cable to track how iceberg calving stirs up warm seawater. The resulting surface tsunamis and massive hidden underwater waves intensify melting at the glacier face. This powerful mixing effect accelerates ice loss far more than previously understood. The work highlights how fragile the Greenland ice system has become as temperatures rise.

Hektoria Glacier’s sudden eight-kilometer collapse stunned scientists, marking the fastest modern ice retreat ever recorded in Antarctica. Its flat, below-sea-level ice plain allowed huge slabs of ice to detach rapidly once retreat began. Seismic activity confirmed this wasn’t just floating ice but grounded mass contributing to sea level rise. The event raises alarms that other fragile glaciers m…

Researchers have created a prediction method that comes startlingly close to real-world results. It works by aiming for strong alignment with actual values rather than simply reducing mistakes. Tests on medical and health data showed it often outperforms classic approaches. The discovery could reshape how scientists make reliable forecasts.

Scientists studying aging found that sensory inputs like touch and smell can cancel out the lifespan-boosting effects of dietary restriction by suppressing the key longevity gene fmo-2. When overactivated, the gene makes worms oddly indifferent to danger and food, suggesting trade-offs between lifespan and behavior. The work highlights how deeply intertwined the brain, metabolism, and environment…

Exercise appears to spark a whole-body anti-aging cascade, and scientists have now mapped out how it happens—and how a simple oral compound can mimic it. By following volunteers through rest, intense workouts, and endurance training, researchers found that the kidneys act as the hidden command center, flooding the body with a metabolite called betaine that restores balance, rejuvenates immune cel…

Ultra-endurance athletes can push their bodies to extraordinary extremes, but even they run into a hard biological wall. Researchers tracked ultra-runners, cyclists, and triathletes over weeks and months, discovering that no matter how intense the effort, the human body maxes out at about 2.5 times its basal metabolic rate when measured long-term. Short bursts of six or seven times BMR are possib…

A newly detected super-Earth just 20 light-years away is giving scientists one of the most promising chances yet to search for life beyond our solar system. The discovery of the exoplanet orbiting in the habitable zone of its star was made possible by advanced spectrographs designed at Penn State and by decades of observations from telescopes around the world.